Wednesday, August 11, 2010

Spherical aberration and higher order aberrations with Balafilcon A (PureVision) and Comfilcon A (Biofinity)

Abstract
Background  
Advances in the optical design of soft contact lenses have seen certain manufacturers incorporate aspheric optics into soft
lenses in an attempt to reduce spherical aberration, to provide superior visual performance. The aim of this study is to determine
the on-eye differences in spherical aberration and higher order aberrations (HOA) between the Bausch and Lomb PureVision (Balafilcon
A) and the CooperVision Biofinity (Comfilcon A).

Methods  
Twenty subjects were recruited in a prospective, randomized, unilateral study. The right eye was dilated and HOA measured
with the NIDEK OPD-Scan. Each eye was fitted randomly with a ?3.00D PureVision and a ?3.00D Biofinity, and HOA were measured
with lenses in situ across a 6 mm pupil. Paired t-tests were performed to determine HOA differences with the lenses in situ compared to baseline.

Results  
Aberrometry was successfully performed on all subjects. Statistical analysis indicated no changes in spherical aberration,
but changes in other HOA. With the PureVision, there were increases in Zernike terms Z31 (from 0.01 ?m to ?0.11 ?m), Z4-2 (from 0.01 ?m to 0.13 ?m) and Z5-1 (from ?0.01 ?m to 0.03 ?m). With the Biofinity there was an increase in Zernike term Z33 (from 0.00 ?m to 0.09 ?m).

Conclusions  
No statistically significant changes occurred in spherical aberration. The PureVision caused statistically significant increases
in Z31, Z4-2 and Z5-1, and the Biofinity caused an increase in Z33. Clinically significant changes (>0.1 ?m) occurred with terms Z31 and Z4-2 with the PureVision only.

  • Content Type Journal Article
  • DOI 10.1007/s00417-010-1476-9
  • Authors
    • Colm McAlinden, School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, BT52 1SA UK
    • Jonathan E. Moore, Cathedral Eye Clinic, University of Ulster, 25-51 York Street, Belfast, BT15 1ED UK
    • Victoria E. McGilligan, School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, BT52 1SA UK
    • Tara C. B. Moore, School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, BT52 1SA UK
    • Journal Graefe’s Archive for Clinical and Experimental Ophthalmology
    • Online ISSN 1435-702X
    • Print ISSN 0721-832X

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